REVEAL（调脂药物Anacetrapib疗效的随机评价）

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试验详情

一、临床试验项目名称
REVEAL（调脂药物Anacetrapib疗效的随机评价）

二、适应症
预防心血管疾病患者的主要血管事件的发生，治疗原发性高胆固醇血症及混合性血脂异常。

三、试验介绍

调脂药物Anacetrapib疗效的随机评价（简称REVEAL）研究，其目的是针对动脉粥样硬化性血管疾病的患者，在他汀降低低密度脂蛋白胆固醇的基础上，评价给予anacetrapib 100mg/日，能否进一步减少冠脉性死亡，心肌梗死或冠脉血管重建（统称主要冠脉事件）的风险。

研究中心所在省份及城市（具体启动情况以后期咨询为准）

研究中心	主要研究者
英国牛津大学	Dr Martin Landray, MB ChB PhD FRCP

序号	机构名称	主要研究者	国家	省（州）	城市
1	中国医学科学院阜外心血管病医院	蒋立新、杨跃进、郑哲、李建军	中国	北京	北京
2	牛津大学	Martin Landray、Louise Bowman	英国	Oxford	Oxford
3	一汽总医院	潘洪涛	中国	吉林	长春
4	上海交通大学医学院苏州九龙医院	刘峰	中国	江苏	苏州
5	吉林省人民医院	杜玉茗、戴绘	中国	吉林	长春
6	吉林市中心医院	钱大为	中国	吉林	吉林
7	吉林大学中日联谊医院	杨萍	中国	吉林	长春
8	北京协和医院	张抒扬	中国	北京	北京
9	北京大学第三医院	李昭屏	中国	北京	北京
10	首都医科大学附属朝阳医院	陈牧雷	中国	北京	北京
11	北京市房山区良乡医院	余清、方雪花	中国	北京	北京
12	天津医科大学总医院	万征	中国	天津	天津
13	天津医科大学第二医院	李新	中国	天津	天津
14	天津市人民医院	张春生、姚朱华	中国	天津	天津
15	天津市第四中心医院	张寰	中国	天津	天津
16	天津市胸科医院	郭绪昆	中国	天津	天津
17	鞍山市钢铁集团公司总医院	刘欣	中国	辽宁	鞍山
18	鞍山市双山医院	肖瑞	中国	辽宁	鞍山
19	中国医科大学附属第一医院鞍山医院	刘斌	中国	辽宁	鞍山
20	辽宁省人民医院	李占全	中国	辽宁	沈阳
21	沈阳市第四人民医院	栗印军	中国	辽宁	沈阳
22	中国医科大学附属第一医院	齐国先	中国	辽宁	沈阳
23	中国医科大学附属盛京医院	马淑梅	中国	辽宁	沈阳
24	沈阳市第一人民医院	冯丰	中国	辽宁	沈阳
25	中国医科大学附属第四医院	金元哲	中国	辽宁	沈阳
26	沈阳市苏家屯区中心医院	车航	中国	辽宁	沈阳
27	沈阳市第五人民医院	刁青	中国	辽宁	沈阳
28	辽宁省沈阳军区总医院	韩雅玲	中国	辽宁	沈阳
29	内蒙古包钢医院	葛智平	中国	内蒙古	包头
30	内蒙古科技大学包头医学院第二附属医院	孙刚	中国	内蒙古	包头
31	包头市中心医院	赵瑞平	中国	内蒙古	包头
32	内蒙古自治区人民医院	韩雅君	中国	内蒙古	呼和浩特
33	内蒙古医学院附属人民医院	刘娟	中国	内蒙古	呼和浩特
34	内蒙古自治区中蒙医医院	苏和	中国	内蒙古	呼和浩特
35	内蒙古呼伦贝尔市人民医院	崔仲华	中国	内蒙古	呼伦贝尔
36	华中科技大学同济医学院附属同济医院	汪道文	中国	湖北	武汉
37	武汉市普爱医院	顾晔	中国	湖北	武汉
38	武汉市中心医院	赵湜	中国	湖北	武汉
39	武汉亚洲心脏病医院	苏晞	中国	湖北	武汉
40	郑州大学第一附属医院	黄振文	中国	河南	郑州
41	郑州市中心医院	张琳	中国	河南	郑州
42	新乡市中心医院	刘玲玲	中国	河南	新乡
43	新乡医学院第一附属医院	吕风华	中国	河南	卫辉
44	第二军医大学长征医院	吴宗贵	中国	上海	上海
45	无锡市人民医院	羊镇宇	中国	江苏	无锡
46	徐州医学院附属医院	李东野	中国	江苏	徐州
47	徐州市中心医院	付强	中国	江苏	徐州
48	徐州市第一人民医院	张鸿举	中国	江苏	徐州
49	徐州医学院第二附属医院	武维恒	中国	江苏	徐州
50	徐州市第三人民医院	王岚英	中国	江苏	徐州
51	大连医科大学第二附属医院	曲鹏	中国	辽宁	大连
52	大连大学附属中山医院	于勤	中国	辽宁	大连
53	大连市第三人民医院	刘晓洁、李楠	中国	辽宁	大连
54	大连市中心医院	智永超	中国	辽宁	大连
55	青岛大学医学院附属医院	周长勇、裴海涛	中国	山东	青岛
56	青岛市立医院东院	王旭	中国	山东	青岛
57	青岛阜外心血管病医院	杨瑛、姜先雁	中国	山东	青岛
58	中南大学湘雅医院	杨天伦	中国	湖南	长沙
59	中南大学湘雅三医院	莫朝晖	中国	湖南	长沙
60	长沙市中心医院	戴海鹰	中国	湖南	长沙
61	湘潭市中心医院	黄河	中国	湖南	湘潭
62	株洲市中心医院	何毅	中国	湖南	株洲
63	哈尔滨医科大学心血管疾病研究所	李为民	中国	黑龙江	哈尔滨
64	哈尔滨医科大学第一临床医学院	张黎明	中国	黑龙江	哈尔滨
65	哈尔滨医科大学附属第二医院	于波、朱雨岚	中国	黑龙江	哈尔滨
66	山西省心血管病医院	李保	中国	山西	太原
67	山西医科大学第一医院	韩清华	中国	山西	太原
68	山西医科大学第二医院	杨志明	中国	山西	太原
69	山西省人民医院	张虹	中国	山西	太原
70	太原市中心医院	陈小平	中国	山西	太原
71	山西省汾阳医院	郭任维	中国	山西	汾阳
72	侯马市人民医院	王志强	中国	山西	侯马
73	吉林大学第一医院	郑杨、王桂侠	中国	吉林	长春
74	Richard Doll Building, Oxford	Dr Anon	UK	Oxford	Oxford
75	Derriford Hospital, Plymouth	Dr Anon	UK	Plymouth	Derriford Hospital
76	Addenbrooke's Hospital, Cambridge	Dr Anon	UK	Cambridge	Cambridge
77	Memorial Hospital, Darlington	Dr Anon	UK	Darlington	Darlington
78	Hillingdon Hospital	Dr Anon	UK	Middlesex	Uxbridge
79	King's Mill Hospital, Sutton-in-Ashfield	Dr Anon	UK	Nottinghamshire	Sutton-in-Ashfield
80	Macclesfield Hospital	Dr Anon	UK	Cheshire East	Macclesfield
81	Pinderfields Hospital, Wakefield	Dr Anon	UK	West Yorkshire	Wakefield
82	Royal United Hospital, Bath	Dr Anon	UK	Bath	Bath
83	Worcestershire Royal Hospital	Dr Anon	UK	Worcester	Worcester
84	Worthing Hospital	Dr Anon	UK	West Sussex	Worthing
85	Bedford Hospital	Dr Anon	UK	Bedford	Bedford
86	St Helier Hospital, Carshalton	Dr Anon	UK	Carshalton	Carshalton
87	Southmead Hospital, Bristol	Dr Anon	UK	Bristol	Bristol
88	Edinburgh Royal Infirmary	Dr Anon	UK	Scotland	Edinburgh
89	Dewsbury District Hospital	Dr Anon	UK	West Yorkshire	Dewsbury
90	Guy's Hospital, London	Dr Anon	UK	London	Great Maze Pond
91	Bristol Royal Infirmary	Dr Anon	UK	Bristol	Bristol
92	Princess Royal Hospital, Telford	Dr Anon	UK	Telford	Wellington
93	Huddersfield Royal Infirmary	Dr Anon	UK	Huddersfield	Huddersfield
94	Manor Hospital, Walsall	Dr Anon	UK	West Midlands	Walsall
95	Aberdeen Royal Infirmary	Dr Anon	UK	Scotland	Aberdeen
96	Birmingham Heartlands Hospital	Dr Anon	UK	West Midlands	Birmingham
97	Northampton General Hospital	Dr Anon	UK	Northampton	Cliftonville
98	North Manchester General Hospital	Dr Anon	UK	Manchester	Manchester
99	Russells Hall Hospital, Dudley	Dr Anon	UK	West Midlands	Dudley
100	Watford General Hospital	Dr Anon	UK	Hertfordshire	Watford
101	Victoria Hospital, Kirkcaldy	Dr Anon	UK	Fife	Kirkcaldy
102	North Tyneside General Hospital, North Shields	Dr Anon	UK	Tyne and Wear	North Shields
103	Sandwell General Hospital	Dr Anon	UK	West Midlands	West Bromwich
104	Royal Victoria Infirmary, Newcastle	Dr Anon	UK	Newcastle upon Tyne	Newcastle upon Tyne
105	Barnsley District General Hospital	Dr Anon	UK	South Yorkshire	Barnsley
106	Royal Bolton Hospital	Dr Anon	UK	Bolton	Farnworth
107	University Hospital of North Staffordshire, Stoke-on-Trent	Dr Anon	UK	Stoke-on-Trent	Stoke-on-Trent
108	Salford Royal Hospital	Dr Anon	UK	Salford	Stott Lane
109	Ninewells Hospital, Dundee	Dr Anon	UK	Dundee	Dundee
110	Rotherham District General Hospital	Dr Anon	UK	South Yorkshire	Rotherham
111	Royal Devon & Exeter Hospital, Exeter	Dr Anon	UK	Exeter	Exeter
112	Southampton General Hospital	Dr Anon	UK	Hampshire	Southampton
113	St Marys Hospital, Portsmouth	Dr Anon	UK	Portsmouth	Portsmouth
114	Musgrove Park Hospital, Taunton	Dr Anon	UK	Somerset	Taunton
115	University Hospital of Wales, Cardiff	Dr Anon	UK	South Wales	Cardiff
116	Torbay Hospital, Torquay	Dr Anon	UK	Torquay	Lawes Bridge
117	Sunderland Royal Hospital	Dr Anon	UK	Tyne and Wear	Sunderland
118	Stepping Hill Hospital, Stockport	Dr Anon	UK	Cheshire	Stockport
119	Victoria Hospital, Blackpool	Dr Anon	UK	Blackpool	Blackpool
120	Whipps Cross University Hospital, London	Dr Anon	UK	Leytonstone	Leytonstone
121	Cheltenham General Hospital	Dr Anon	UK	Gloucestershire	Cheltenham
122	Colwyn Bay Community Hospital	Dr Anon	UK	Wales	Colwyn Bay
123	Royal Cornwall Hospital, Truro	Dr Anon	UK	Cornwall	Truro
124	Queen's Hospital, Burton-upon-Trent	Dr Anon	UK	Staffordshire	Burton-on-Trent
125	Royal Blackburn Hospital	Dr Anon	UK	Lancashire	Blackburn
126	St Richard's Hospital, Chichester	Dr Anon	UK	West Sussex	Chichester
127	Royal Berkshire Hospital	Dr Anon	UK	Reading	Reading
128	Yeovil District Hospital	Dr Anon	UK	Somerset	Yeovil
129	Bradford Royal Infirmary	Dr Anon	UK	Bradford	Duckworth Lane
130	Wythenshawe Hospital	Dr Anon	UK	Manchester	Manchester
131	Lister Hospital, Stevenage	Dr Anon	UK	Hertfordshire	Stevenage
132	Luton and Dunstable Hospital	Dr Anon	UK	Luton	Luton
133	Queen's Medical Centre, Nottingham	Dr Anon	UK	Nottingham	Nottingham
134	University Hospital, Coventry	Dr Anon	UK	West Midlands	Coventry
135	West Cumberland Hospital, Whitehaven	Dr Anon	UK	Cumbria	Whitehaven
136	Dorset County Hospital, Dorchester	Dr Anon	UK	Dorchester	Dorchester
137	Kuopion liikuntalaaketieteen tutkimuslaitos	Dr Anon	Finland	Oulu	Oulu
138	Kuopion liikuntalaaketieteen tutkimuslaitos	Dr Anon	Finland	Kuopio	Kuopio
139	CorusFit Oy, Jyvaskyla	Dr Anon	Finland	Jyvaskyla	Jyvaskyla
140	Kuusankosken terveysasema	Dr Anon	Finland	Kuusankoski	Kuusankoski
141	Etela-Karjalan keskussairaala	Dr Anon	Finland	Lappeenranta	Lappeenranta
142	Geri-Med Oy	Dr Anon	Finland	Helsinki	Helsinki
143	Seinajoen Laakaritalo	Dr Anon	Finland	Seinajoki	Seinajoki
144	Turun yliopistollinen sairaala/Sisatautien klinikka	Dr Anon	Finland	Turku	Turku
145	FinnMedi Oy	Dr Anon	Finland	Tampere	Tampere
146	Lapin keskussairaala	Dr Anon	Finland	Rovaniemi	Rovaniemi
147	Pohjois-Karjala Projektisaatio	Dr Anon	Finland	Joensuu	Joensuu
148	Linkopings Universitetssjukhus	Dr Anon	Sweden	Linkoping	Linkoping
149	Vaxjo Sjukhus	Dr Anon	Sweden	Vaxjo	Vaxjo
150	Dalecarlia clinical RC	Dr Anon	Sweden	Rattvik	Rattvik
151	Ljungby Lasarett	Dr Anon	Sweden	Ljungby	Ljungby
152	Centralsjukhuset Kristianstad	Dr Anon	Sweden	Kristianstad	Kristianstad
153	Capio Lund	Dr Anon	Sweden	Lund	Lund
154	Prim Site	Dr Anon	Sweden	Orebro	Orebro
155	City Heart	Dr Anon	Sweden	Stockholm	Stockholm
156	Skelleftea Lasarett	Dr Anon	Sweden	Skelleftea	Skelleftea
157	Hassleholms Sjukhus	Dr Anon	Sweden	Hassleholm	Hassleholm
158	Oskarshamns Sjukhus	Dr Anon	Sweden	Oskarshamn	Oskarshamn
159	Stockholm Heart Center	Dr Anon	Sweden	Stockholm	Stockholm
160	Norrlands Universitetssjukhus	Dr Anon	Sweden	Umea	Umea
161	Obackakliniken	Dr Anon	Sweden	Harnosand	Harnosand
162	Molndals Sjukhus	Dr Anon	Sweden	Molndal	Molndal
163	Halmstads Sjukhus	Dr Anon	Sweden	Halmstad	Halmstad
164	Karolinska Universitetssjukhuset	Dr Anon	Sweden	Stockholm	Stockholm
165	Motala lasarett	Dr Anon	Sweden	Motala	Motala
166	Ulleval universitetssykehus HF	Dr Anon	Norway	Oslo	Oslo
167	Skedsmo Medisinske Senter AS	Dr Anon	Norway	Skedsmokorset	Skedsmokorset
168	Sykehuset Innlandet HF Hamar	Dr Anon	Norway	Hamar	Hamar
169	Sykehuset Innlandet HF Lillehammer	Dr Anon	Norway	Lillehammer	Lillehammer
170	Stavanger Helseforskning AS	Dr Anon	Norway	Stavanger	Stavanger
171	Haugesund Hjertepraksis	Dr Anon	Norway	Haugesund	Haugesund
172	Haukeland Universitetssykehus	Dr Anon	Norway	Bergen	Bergen
173	Sykehuset Innlandet HF, Kongsvinger	Dr Anon	Norway	Kongsvinger	Kongsvinger
174	Forde sentralsjukehus	Dr Anon	Norway	Forde	Forde
175	Sykehuset Telemark, HF Skien	Dr Anon	Norway	Skien	Skien
176	UNN Hjerte/kar poliklinikk	Dr Anon	Norway	Tromso	Tromso
177	MEDI3 Alesund	Dr Anon	Norway	Alesund	Alesund
178	Nordland Hjertesenter AS	Dr Anon	Norway	Bodo	Bodo
179	Vestfold Hjertesenter AS	Dr Anon	Norway	Sandefjord	Sandefjord
180	Norsk Helseklinikk	Dr Anon	Norway	Lierskogen	Lierskogen
181	St. Olavs Hospital	Dr Anon	Norway	Trondheim	Trondheim
182	Ulleval universitetssykehus HF #2	Dr Anon	Norway	Oslo	Oslo
183	Svendborg Hospital	Dr Anon	Denmark	Svendborg	Svendborg
184	Esbjerg Hospital	Dr Anon	Denmark	Esbjerg	Esbjerg
185	Roskilde Hospital	Dr Anon	Denmark	Roskilde	Roskilde
186	Kolding Hospital	Dr Anon	Denmark	Kolding	Kolding
187	Viborg Hospital	Dr Anon	Denmark	Viborg	Viborg
188	Holbaek Hospital	Dr Anon	Denmark	Holbaek	Holbaek
189	Herning Hospital	Dr Anon	Denmark	Herning	Herning
190	Gentofte Sygehus	Dr Anon	Denmark	Hellerup	Hellerup
191	Rigshospitalet Copenhagen	Dr Anon	Denmark	Kobenhavn O	Kobenhavn O
192	Nordsjaellands Hospital-Sundhedshuset, Helsingor	Dr Anon	Denmark	Helsingior	Helsingior
193	Aalborg Hospital	Dr Anon	Denmark	Aalborg	Aalborg
194	Skejby Hospital	Dr Anon	Denmark	Arhus N	Arhus N
195	Silkeborg Hospital	Dr Anon	Denmark	Silkeborg	Silkeborg
196	Odense Universitets hospital	Dr Anon	Denmark	Odense C	Odense C
197	Steno Diabetes center	Dr Anon	Denmark	Gentofte	Gentofte
198	Glostrup Hospital	Dr Anon	Denmark	Glostrup	Glostrup
199	Kolesterollaboratoriet, Gentofte	Dr Anon	Denmark	Hellerup	Hellerup
200	Slagelse hospital	Dr Anon	Denmark	Slagelse	Slagelse
201	Naestved hospital	Dr Anon	Denmark	Naestved	Naestved
202	Mobile Heart Specialists, PC	Dr Anon	USA	Alabama	Mobile
203	Louisville Metabolic and Atherosclerosis Research Center (L-MARC)	Dr Anon	USA	Kentucky	Louisville
204	UCH-MHS	Dr Anon	USA	Colorado	Colorado Springs
205	Hudson Valley Cardiovascular Practice, P.C	Dr Anon	USA	New York	Poughkeepsie
206	Santa Rosa Cardiology Medical Group, Inc.	Dr Anon	USA	California	Santa Rosa
207	Premier Healthcare, LLC	Dr Anon	USA	Indiana	Bloomington
208	Verde Valley Medical Center	Dr Anon	USA	Arizona	Cottonwood
209	NYU Hudson Valley Cardiology	Dr Anon	USA	New York	Cortlandt Manor
210	Gotham Cardiovascular Research	Dr Anon	USA	New York	New York
211	Clinical Trials of America, INC.	Dr Anon	USA	North Carolina	Hickory
212	Associated Research Partners LLC	Dr Anon	USA	Arkansas	Jonesboro
213	Community Clinical Research Center	Dr Anon	USA	Indiana	Anderson
214	Marin Endocrine Care Research	Dr Anon	USA	California	Greenbrae
215	Overlake Medical Clinics Cardiology	Dr Anon	USA	Washington	Bellevue
216	Capital Cardiology Associates (Troy)	Dr Anon	USA	New York	Troy
217	Eastern Suffolk Cardiology	Dr Anon	USA	New York	Southampton
218	MidValley Cardiology	Dr Anon	USA	New York	Kingston
219	Asheville Cardiology Associates	Dr Anon	USA	North Carolina	Asheville
220	Charles River Medical Associates	Dr Anon	USA	Massachusetts	Natick
221	Saratoga Cardiology Assoc., PC/Saratoga Clinical Research, LLC	Dr Anon	USA	New York	Saratoga Springs
222	Southwest Heart	Dr Anon	USA	Arizona	Tucson
223	Brigham and Women's Hospital	Dr Anon	USA	Massachusetts	Boston
224	Cardiology Associates of Bellin Health	Dr Anon	USA	Wisconsin	Green Bay
225	The Center for Pharmaceutical Research, P.C.	Dr Anon	USA	Missouri	Kansas City
226	Bryan Heart	Dr Anon	USA	Nebraska	Lincoln
227	Kore CV Research	Dr Anon	USA	Tennessee	Jackson
228	Cardiology Associates of Fairfield County, P.C. (Dr Anon)	Dr Anon	USA	Connecticut	Stamford
229	DCA Research, LLC	Dr Anon	USA	Florida	Fort Lauderdale
230	Acadia Clinical Research LLC	Dr Anon	USA	Maine	Bangor
231	Comprehensive Cardiovascular Medical Group	Dr Anon	USA	California	Bakersfield
232	University of Alabama Medical Center	Dr Anon	USA	Alabama	Birmingham
233	Cardiology Associates of Fairfield County, P.C. (Dr Anon)	Dr Anon	USA	Connecticut	Trumbull, CT
234	Cardiology Associates of Fairfield County, P.C. (Dr Anon)	Dr Anon	USA	Connecticut	Norwalk
235	Texas Cardiology Research Center PLLC	Dr Anon	USA	Texas	Kingwood
236	Central Bucks Cardiology	Dr Anon	USA	Pennsylvania	Doylestown
237	Kootenai Heart Clinics, LLC (Dr Anon)	Dr Anon	USA	Idaho	Coeur d' Alene
238	Capital Cardiology Associates (Albany)	Dr Anon	USA	New York	Albany
239	Wenatchee Valley Hospital and Clinics	Dr Anon	USA	Washington	Wenatchee
240	Heart Center at St. Mark's Hospital	Dr Anon	USA	Utah	Salt Lake City
241	Clinical Research Associates	Dr Anon	USA	South Carolina	Florence
242	South Oklahoma Heart Research, LLC	Dr Anon	USA	Oklahoma	Oklahoma City
243	Austin Heart, PLLC	Dr Anon	USA	Texas	Austin
244	MultiCare Health System Research Institute	Dr Anon	USA	Washington	Tacoma
245	Parkview Research Center	Dr Anon	USA	Indiana	Fort Wayne
246	MultiCare Research Institute	Dr Anon	USA	Washington	Tacoma
247	Boice Willis Clinic	Dr Anon	USA	North Carolina	Rocky Mount
248	Escondido Cardiology Associates, Inc	Dr Anon	USA	California	Escondido
249	Albany Associates in Cardiology	Dr Anon	USA	New York	Albany
250	Upstate Cardiology	Dr Anon	USA	South Carolina	Greenville
251	Intermed, PA	Dr Anon	USA	Maine	Portland
252	Maine Research Associates	Dr Anon	USA	Maine	Auburn
253	Cardiovascular Research of Knoxville	Dr Anon	USA	Tennessee	Knoxville
254	Nebraska Heart Institute (Dr Anon)	Dr Anon	USA	Nebraska	Lincoln
255	Northern Michigan Regional Hospital (Nisus Research)	Dr Anon	USA	Michigan	Petoskey
256	Heart Center Research LLC (Dr Anon)	Dr Anon	USA	Alabama	Huntsville
257	Norton Cardiovascular Associates (Dr Anon)	Dr Anon	USA	Kentucky	Louisville
258	Cardiovascular Associates of the Southeast, LLC (Dr Anon)	Dr Anon	USA	Alabama	Birmingham
259	Cardiovascular Associates of the Southeast, LLC. (Dr Anon)	Dr Anon	USA	Alabama	Birmingham
260	Carient Heart and Vascular (Dr Anon)	Dr Anon	USA	Virginia	Manassas
261	Pentucket Medical Associates	Dr Anon	USA	Massachusetts	Haverhill
262	Grand View-Lehigh Valley Health Services, Buxmont Cardiology Division	Dr Anon	USA	Pennsylvania	Sellersville
263	Prevea Clinic, Inc. (Dr Anon)	Dr Anon	USA	Wisconsin	Green Bay
264	Albuquerque Clinical Trials, Inc.	Dr Anon	USA	New Mexico	Albuquerque
265	Kootenai Heart Clinics, LLC	Dr Anon	USA	Washington	Spokane
266	Tenet Florida Physician Services	Dr Anon	USA	Florida	Jupiter
267	Chesapeake Cardiovascular Associates	Dr Anon	USA	Maryland	Baltimore
268	East Texas Cardiology, PA	Dr Anon	USA	Texas	Houston
269	Permian Research Foundation	Dr Anon	USA	Texas	Odessa
270	Imperial Health, LLP	Dr Anon	USA	Louisiana	Lake Charles
271	Palmetto Research Center, LLC	Dr Anon	USA	South Carolina	Spartanburg
272	Cleveland Cardiovascular Research Foundation	Dr Anon	USA	Ohio	Fairview Park
273	Northwest Heart Clinical Research, LLC	Dr Anon	USA	Lllinois	Arlington Heights
274	University of Missouri Health System (Dr Anon)	Dr Anon	USA	Missouri	Columbia
275	Iowa Diabetes and Endocrinology Research Center (Dr Anon)	Dr Anon	USA	Iowa	Des Moines
276	Gemini Scientific, LLC (Dr Anon)	Dr Anon	USA	Wisconsin	Madison
277	Michigan Cardiovascular Institute (Dr Anon)	Dr Anon	USA	Michigan	Saginaw
278	MidMichigan Medical Center Midland (Dr Anon)	Dr Anon	USA	Michigan	Midland
279	Virginia Heart (Dr Anon)	Dr Anon	USA	Virginia	Falls Church
280	North Alabama Research Center, LLC (Dr Anon)	Dr Anon	USA	Alabama	Athens
281	National Clinical Research-Richmond, Inc (Dr Anon)	Dr Anon	USA	Virginia	Richmond
282	PriMed Physicians, A Member of Northeast Medical Group, Yale New Haven Health	Dr Anon	USA	Connecticut	Trumbull
283	Black Hills Cardiovascular Research (Dr Anon)	Dr Anon	USA	South Dakota	Rapid City
284	LeBauer Cardiovascular Research Foundation	Dr Anon	USA	North Carolina	Greensboro
285	Dayton Heart Center	Dr Anon	USA	Ohio	Dayton
286	Clinical Trials of America (Shreveport)	Dr Anon	USA	Louisiana	Shreveport
287	Chesapeake Cardiovascular Associates (Dr Anon)	Dr Anon	USA	Maryland	Towson
288	Overlea Personal Physicians	Dr Anon	USA	Maryland	Baltimore
289	HeartCare Midwest	Dr Anon	USA	Illinois	Peoria
290	Pottstown Medical Specialists, Inc. (PMSI)	Dr Anon	USA	Pennsylvania	Pottstown
291	Green and Seidner Family Practice Associates	Dr Anon	USA	Pennsylvania	Lansdale
292	Cardiovascular Research Foundation of Southern California	Dr Anon	USA	California	Beverly Hills
293	Westlake Medical Research	Dr Anon	USA	California	Thousand Oaks
294	Providence Saint Joseph Medical Center	Dr Anon	USA	California	Burbank
295	Austin Heart, PLLC (Dr Anon)	Dr Anon	USA	Texas	San Marcos
296	Heritage Valley Medical Group, Inc.	Dr Anon	USA	Pennsylvania	Beaver
297	Oregon Health & Science University	Dr Anon	USA	Oregon	Portland
298	Lutherville Personal Physicians	Dr Anon	USA	Maryland	Lutherville
299	Dr Anon Research Network, LLC	Dr Anon	USA	Ohio	Marion
300	Novant Health Heart and Vascular Institute	Dr Anon	USA	North Carolina	Charlotte
301	Cardiovascular Institute of the South	Dr Anon	USA	Louisiana	Opelousas
302	HOPE Research Institute	Dr Anon	USA	Arizona	Phoenix
303	Baylor College of Medicine (Center for Cardiovascular Disease Prevention)	Dr Anon	USA	Texas	Houston
304	Trinity Medical Center (Rock Island)	Dr Anon	USA	Illinois	Rock Island
305	North Ohio Research Ltd	Dr Anon	USA	Ohio	Sandusky
306	The Lindner Center for Research & Education at The Christ Hospital	Dr Anon	USA	Ohio	Cincinnati
307	OhioHealth Research Institute	Dr Anon	USA	Ohio	Mansfield
308	Beverly Hills Heart Center	Dr Anon	USA	California	Los Angeles
309	Hope Research Institute (Einhorn)	Dr Anon	USA	Arizona	Chandler
310	University of Maryland	Dr Anon	USA	Maryland	Westminster
311	MODEL Clinical Research	Dr Anon	USA	Maryland	Baltimore
312	York Hospital	Dr Anon	USA	Pennsylvania	York
313	Brigham and Women's Hospital (Cannon)	Dr Anon	USA	Massachusetts	Boston
314	Chesapeake Cardiovascular Associates (Peichert)	Dr Anon	USA	Maryland	Baltimore
315	Harrisonburg Medical Associates (Dr Anon)	Dr Anon	USA	Virginia	Harrisonburg
316	Buffalo Cardiology and Pulmonary Associates, P.C.	Dr Anon	USA	New York	Williamsville
317	The University of Iowa, College of Public Health,Preventive Intervention Center	Dr Anon	USA	Iowa	Iowa City
318	Advanced Neurology Specialists	Dr Anon	USA	Montana	Great Falls
319	The Polyclinic	Dr Anon	USA	Washington	Seattle
320	Aventura Heart Center	Dr Anon	USA	Florida	Aventura
321	Westside Center for Clinical Research	Dr Anon	USA	Florida	Jacksonville
322	Health First Inc.	Dr Anon	USA	Florida	Melbourne
323	Associated Cardiovascular Consultants	Dr Anon	USA	New Jersey	Voorhees
324	Cardiovascular Associates of the Delaware Valley, PA- Elmer	Dr Anon	USA	New Jersey	Elmer
325	Research Physicians Network Alliance- Hollywood	Dr Anon	USA	Florida	Hollywood
326	Research Physicians Network Alliance- Pembroke Pines	Dr Anon	USA	Florida	Pembroke Pines
327	Cohen Medical Associates	Dr Anon	USA	Florida	Delray Beach
328	NJ Heart	Dr Anon	USA	New Jersey	Linden
329	St. Johns Center For Clinical Research	Dr Anon	USA	Florida	Ponte Vedra
330	Charlotte Heart Group Research Center	Dr Anon	USA	Florida	Port Charlotte
331	Cardiovascular Associates of the Delaware Valley, PA- Haddon Heights	Dr Anon	USA	New Jersey	Haddon Heights
332	Cardiovascular Associates of the Delaware Valley, PA- Sewell	Dr Anon	USA	New Jersey	Sewell
333	Tallahassee Research Institute Inc.	Dr Anon	USA	Florida	Tallahassee
334	Jacksonville Center for Clinical Research	Dr Anon	USA	Florida	Jacksonville
335	Southwest Florida Research	Dr Anon	USA	Florida	Naples
336	Atlanta Heart Specialists, LLC	Dr Anon	USA	Georgia	Cumming
337	Bay Area Cardiology Associates P.A.	Dr Anon	USA	Florida	Brandon
338	Watson Clinic Center for Research	Dr Anon	USA	Florida	Lakeland
339	Cardiology Research Associates	Dr Anon	USA	Florida	Daytona Beach
340	Medicor Cardiology	Dr Anon	USA	New Jersey	Bridgewater
341	Clearwater Cardiovascular and Interventional Consultants	Dr Anon	USA	Florida	Clearwater
342	Florida Hospital	Dr Anon	USA	Florida	Orlando
343	South Florida Research Group LLC	Dr Anon	USA	Florida	Miami
344	Advanced Heart Care, LLC	Dr Anon	USA	New Jersey	Bridgewater
345	G&G Research Inc.	Dr Anon	USA	Florida	Vero Beach
346	Ocala Research Institute, INC	Dr Anon	USA	Florida	Ocala
347	Cardiology Consultants	Dr Anon	USA	Florida	Pensacola
348	Clearwater Cardiovascular and Interventional Consultants (Dr Anon)	Dr Anon	USA	Florida	Safety Harbor
349	Clinical Trials of America, Inc (Lenoir)	Dr Anon	USA	North Carolina	Lenoir
350	Regions Hospital-Health Partners (Dr Anon)	Dr Anon	USA	Minnesota	St. Paul
351	CentraCare Heart and Vascular Center at St. Cloud Hospital (Dr Anon)	Dr Anon	USA	Minnesota	St. Cloud
352	Meriter Medical Group, Inc. DBA: Meriter Wisconsin Heart (Dr Anon)	Dr Anon	USA	Wisconsin	Madison
353	Q&T Research Outaouais Incorporated	Dr Anon	Canada	Quebec	Gatineau, QC
354	Newmarket Cardiology Research Group	Dr Anon	Canada	Ontario	Newmarket
355	Dr Anon Cardiac Research	Dr Anon	Canada	Ontario	Cambridge
356	Cambridge Cardiac Care Inc.	Dr Anon	Canada	Ontario	Cambridge
357	Discovery Clinical Services LTD	Dr Anon	Canada	British Columbia	Victoria
358	Dr Anon MD	Dr Anon	Canada	Ontario	Oshawa
359	Oshawa Clinic	Dr Anon	Canada	Ontario	Oshawa
360	Clinique Sante Cardio MC	Dr Anon	Canada	Quebec	Montreal
361	CSSSNL/CHRDL	Dr Anon	Canada	Quebec	Saint-Charles-Borromee
362	Centre de Recherche Medialpha	Dr Anon	Canada	Quebec	St. Lachine
363	Centre de Depistage et Recherche Cardiovasculaire Rive-Sud	Dr Anon	Canada	Quebec	Longueuil
364	Brampton Research Associates	Dr Anon	Canada	Ontario	Brampton
365	Dr Anon, Inc	Dr Anon	Canada	British Columbia	Surrey
366	Centre de Sante et de Services Sociaux du Sud de Lanaudiere-Hopital Pierre-Le Ga	Dr Anon	Canada	Quebec	Terrebonne
367	Heart Care Research	Dr Anon	Canada	Ontario	Oshawa
368	Heritage Medical Research Clinic	Dr Anon	Canada	Alberta	Calgary
369	Viacar Recherche Clinique Inc.	Dr Anon	Canada	Quebec	Greenfield Park
370	Bologna - Ospedale Maggiore	Dr Anon	Italy	Bologna	Bologna
371	Orbassano - Ospedale San Luigi Gonzaga	Dr Anon	Italy	Orbassano	Orbassano
372	Pavia - Fondazione Salvatore Maugeri	Dr Anon	Italy	Pavia	Pavia
373	Sarzana - Ospedale San Bartolomeo	Dr Anon	Italy	La Spezia	Sarzana
374	Albano Laziale - Ospedali Riuniti Albano-Genzano	Dr Anon	Italy	Rome	Albano Laziale
375	Lido di Camaiore - Nuovo Ospedale Versilia	Dr Anon	Italy	Lucca	Lido di Camaiore
376	Terni - Azienda USL 2	Dr Anon	Italy	Terni	Terni
377	Aosta - Ospedale Generale Regionale U.Parini	Dr Anon	Italy	Aosta Valley	Aosta
378	Sondrio - Ospedale Civile	Dr Anon	Italy	Sondrio	Sondrio
379	Milano - Ospedale Niguarda	Dr Anon	Italy	Milano	Milano
380	Legnano - Ospedale Civile	Dr Anon	Italy	Legnano	Legnano
381	Cremona - Istituti Ospitalieri	Dr Anon	Italy	Cremona	Cremona
382	Palmanova - Ospedale di Palmanova	Dr Anon	Italy	Udine	Palmanova
383	Rimini - Ospedale Infermi	Dr Anon	Italy	Rimini	Rimini
384	Firenze - Ospedale San Giovanni di Dio	Dr Anon	Italy	Florence	Firenze
385	Cortona - Ospedale Valdichiana Santa Margherita	Dr Anon	Italy	Arezzo	Cortona
386	Gubbio - Ospedale Gubbio Gualdo Tadino	Dr Anon	Italy	Perugia	Gualdo Tadino
387	Santa Maria Capua Vetere - Ospedale San Giuseppe e Melorio	Dr Anon	Italy	Caserta	Santa Maria Capua Vetere
388	San Felice a Cancello - Ospedale Ave Gratia Plena	Dr Anon	Italy	Caserta	San Felice a Cancello
389	Bari - Ospedale San Paolo	Dr Anon	Italy	Bari	Bari
390	Foggia - Ospedali Riuniti	Dr Anon	Italy	Foggia	Foggia
391	Casarano - Presidio Ospedaliero F.Ferrari	Dr Anon	Italy	Lecce	Casarano
392	Scorrano - Ospedale Ignazio Veris delli Ponti	Dr Anon	Italy	Lecce	Scorrano
393	Veruno - Fondazione Salvatore Maugeri	Dr Anon	Italy	Veruno	Veruno
394	Udine - AOU Santa Maria della Misericordia	Dr Anon	Italy	Udine	Udine
395	Isernia - Ospedale F. Veneziale	Dr Anon	Italy	Isernia	Isernia
396	Deutsches Zentrum fur Herzinsuffizienz	Dr Anon	Germany	Wuerzburg	Wuerzburg
397	SLK-Kliniken Heilbronn	Dr Anon	Germany	Bad Friedrichshall	Bad Friedrichshall
398	Vivantes Klinikum am Urban	Dr Anon	Germany	Berlin	Berlin
399	Charite Campus Virchow-Klinikum	Dr Anon	Germany	Berlin	Berlin
400	Juedisches Krankenhaus Berlin	Dr Anon	Germany	Berlin	Berlin
401	Klinikum Bielefeld	Dr Anon	Germany	Bielefeld	Bielefeld
402	Universitaetsklinikum Bonn	Dr Anon	Germany	Bonn	Bonn
403	Klinikum Coburg gGmbH	Dr Anon	Germany	Coburg	Coburg
404	St. Johannes Hospital Dortmund	Dr Anon	Germany	Dortmund	Dortmund
405	Gefass Zentrum Universitatsklinik Dresden	Dr Anon	Germany	Dresden	Dresden
406	Klinikum Frankfurt Hoechst	Dr Anon	Germany	Frankfurt a. M.	Frankfurt a. M.
407	Universitaetsklinikum Hamburg GmbH	Dr Anon	Germany	Hamburg	Hamburg
408	Medizinische Hochschule Hannover	Dr Anon	Germany	Hannover	Hannover
409	Klinikum Leverkusen gGmbH	Dr Anon	Germany	Leverkusen	Leverkusen
410	Kardiologie Universitat Magdeburg	Dr Anon	Germany	Magdeburg	Magdeburg
411	Cardiopraxis Mainz	Dr Anon	Germany	Mainz	Mainz
412	Klinikum Universitaet Muenchen-Grosshadern	Dr Anon	Germany	Muenchen	Muenchen
413	Klinikum der Universitat München - Campus Innenstadt	Dr Anon	Germany	Muenchen	Muenchen
414	Kardiologische Gemeinschaftspraxis Prof. Silber	Dr Anon	Germany	Muenchen	Muenchen
415	Gemeinschaftspraxis Dr Anon	Dr Anon	Germany	Nuernberg	Nuernberg
416	Uniklinikum Regensburg	Dr Anon	Germany	Regensburg	Regensburg
417	Klinik am See	Dr Anon	Germany	Ruedersdorf	Ruedersdorf
418	Robert Bosch Krankenhaus	Dr Anon	Germany	Stuttgart	Stuttgart
419	Forschungszentrum Ruhr	Dr Anon	Germany	Witten	Witten
420	Praxis fur Kardiologie Dr Anon	Dr Anon	Germany	Muenchen	Muenchen
421	Kardiologische Gemeinschaftspraxis Wuerzburg	Dr Anon	Germany	Wuerzburg	Wuerzburg
422	Universitats-Herzzentrum Freiburg-Bad Krozingen	Dr Anon	Germany	Bad Krozingen	Bad Krozingen
423	Universitaet Magdeburg Lipidambulanz	Dr Anon	Germany	Magdeburg	Magdeburg
424	Universitaetsklinikum Muenster Lipidambulanz	Dr Anon	Germany	Muenster	Muenster
425	DRK Kliniken Berlin	Dr Anon	Germany	Berlin	Berlin
426	Ambulantes Herzzentrum Kassel	Dr Anon	Germany	Kassel	Kassel

1	患者被邀请参加研究时年龄必须≥50岁，且至少符合下列入选标准中的一项：
2	心肌梗死病史；或
3	脑血管动脉粥样硬化性疾病（即推测的缺血性脑卒中或颈动脉血管重建术病史）；或
4	外周动脉性疾病（即非冠状动脉血管重建术病史，包括主动脉瘤修复术或人工血管旁路移植术）；或
5	糖尿病且有其它症状性冠心病的证据（即因心绞痛接受治疗或住院，或冠脉血管重建或急性冠脉综合征病史）。

1	没有下列任何一项：
2	筛查门诊前4周内或导入期发生急性心肌梗死、急性冠脉综合征或脑卒中（这些患者日后如果合适，仍可入选）；
3	计划6个月内实施血管重建术（这些患者日后如果合适，仍可入选）；
4	明确的慢性肝病史，或肝功能异常（即ALT > 2 倍ULN）；（注：有急性肝炎病史患者，只要 ALT不超过此范围即可入选）；
5	严重肾功能不全（即肌酐>200 μmol/L[2.3 mg/dl]，透析或肾移植）；
6	有活动性炎性肌病的证据（如皮肌炎，多发性肌炎），或CK >3倍正常上限；
7	既往对他汀或anacetrapib有明确不良反应；
8	目前正在使用下列降脂药物：（i）在非亚洲国家较阿托伐他汀80mg/日，在东北亚国家较阿托伐他汀20mg/日更强效的降LDL-C药物；或（ii）纤维酸衍生物（“贝特类”，包括吉非贝特）；或（iii）烟酸（尼古丁酸），剂量大于100 mg/日
9	使用与anacetrapib 或阿托伐他汀禁忌的药物（i）任何高效的CYP3A4 抑制剂，包括：（a）大环内酯类抗生素（红霉素，克拉霉素，泰利霉素）；（b）全身使用咪唑类或三唑类抗真菌药（如伊曲康唑，泊沙康唑）；（c）蛋白酶抑制剂（如阿扎那韦）；（d）萘法唑酮；（ii）环孢素（iii）达托霉素；（iv) 全身使用夫西地酸（注：短期服用这些药物的患者，如符合其它条件，停用上述药物后，可再次筛选）；
10	已知对研究随访或研究药物依从性差；
11	存在可能限制患者完成研究期间服用研究药物的疾病史（如严重呼吸系统疾病、近5年内有除非黑色素瘤皮肤癌以外的癌症或癌症扩散依据、近期酗酒或滥用药物史）；
12	育龄期女性（除外已有效避孕者）
13	目前正在参加未上市药物或设备的临床试验
14	在筛查门诊时，需排除即使服用该地区可用的阿托伐他汀最大剂量（非亚洲国家80mg/日，东北亚国家20mg/日）仍可能无法将总胆固醇降至3.5mmol/L（135mg/dl）以下的患者。
15	此外，在随机门诊时需排除以下情况的患者：总胆固醇高于4mmol/L（155mg/dl）；导入期服药依从性差（实际服用研究药物量少于应服药物量的90%）；患者不再愿意随机进入4-5年的研究；患者的医生认为患者不应被随机。

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